 |
| 产品货号 | IM001-0020 | 包装量 | 100μl |
| 名称 | ATF2 (Phospho-Thr69 or 51) Antibody | 储存条件 | Store at -20°C/1 year |
| 应用 | IHC IF | 来源 | 兔多克隆抗体 |
| 种属反应性 | 人、小鼠、大鼠 | 分子量 | 65-75KD |
Description: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | |||
Specificity:The antibody detects endogenous level of ATF-2 only when phosphorylated at threonine 69 or 51 | |||
Immunogen:Peptide sequence around phosphorylation site of threonine 69 or 51 (D-Q-T(p)-P-T) derived from Human ATF2. | |||
Formulation: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | |||
Synonyms: CREB2, CREBP1 | |||
Background:Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex. | |||
| Recommended Dilutions: Immunohistochemistry: 1:50~1:100 | |||
This product is intended for research purposes only. This product is not intended to be used for therapeutic or diagnostic purposes in humans or animals | |||
