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ExCell(CB) CB055-1541 Granzyme B, Mouse

ExCell(CB) CB055-1541 Granzyme B, Mouse 10.0ug 上海有现货,数量500个

  • 商品编号:01.ExCell(CB).CB055-1541
  • 货号:01.ExCell(CB).CB055-1541
  • 品  牌:ExCell(CB)
  • 计量单位:
  • 所得积分:420
  • 市场价: ¥1050.00
  • 销售价: ¥840.00
  • 节省:¥210.00
  • 广州仓库:无现货  上海仓库:有现货  北京仓库:无现货
    (库存情况仅供参考,请来电确认准确的现货情况)
  • 本商品仅供科研之用,不可用于临床
品牌:ExCell(CB)
货号:CB055-1541
规格:10.0μg
表达系统:CHO
内毒素:< 0.2 EU/μg, determined by LAL method.
生物活性:Measured by its ability to cleave a chromogenic peptide substrate (Ac-IEPD-pNA), the specific activity is greater than 1000 nM/min per μg of enzyme.
保存条件:-80℃
保存时间:1年
应用:Growth/Differentiation
产品描述:Granzyme B is a serine protease most commonly found in the granules of cytotoxic lymphocytes (CTLs), natural killer cells (NK cells) and cytotoxic T cells. It is secreted by these cells along with the pore forming protein perforin to mediate apoptosis in target cells.
Granzyme B has also recently been found to be produced by a wide range of non-cytotoxic cells ranging from basophils and mast cells to smooth muscle cells. The secondary functions of granzyme B are also numerous. Granzyme B has been shown to be involved in inducing inflammation by stimulating cytokine release and is also involved in extracellular matrix remodeling.
Recombinant Mouse Granzyme B produced in CHO cells is a polypeptide chain containing 227 amino acids. A fully biologically active molecule, rmGranzyme B has a molecular mass of 32 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at ExCell Bio.

 

 
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