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ExCell(CB) CB055-2021 IL-8/CXCL8 (8-79aa), Human

ExCell(CB) CB055-2021 IL-8/CXCL8 (8-79aa), Human 10.0ug 上海有现货,数量500个

  • 商品编号:01.ExCell(CB).CB055-2021
  • 货号:01.ExCell(CB).CB055-2021
  • 品  牌:ExCell(CB)
  • 计量单位:
  • 所得积分:300
  • 市场价: ¥750.00
  • 销售价: ¥600.00
  • 节省:¥150.00
  • 广州仓库:无现货  上海仓库:有现货  北京仓库:无现货
    (库存情况仅供参考,请来电确认准确的现货情况)
  • 本商品仅供科研之用,不可用于临床
品牌:  ExCell(CB)
货号:CB055-2021
规格:10.0μg
表达系统:E. coli
内毒素:< 0.2 EU/μg, determined by LAL method.
生物活性:ED50 < 20 ng/mL, measured by the FLIPR assay using CHO cells transfected with human CXCR1, the receptor of human CXCL8, corresponding to a specific activity of > 5×104 units/mg.
保存条件:-80℃
保存时间:1年
应用:Growth/Differentiation
产品描述:Interleukin-8 is one of the first discovered chemokines, and belongs to the CXCL family, in which the first two conserved cysteines are separated by one residue. In vivo, IL-8 exists in two forms: 77 a.a. produced by endothelial cells, and the more active 72 a.a. produced by monocytes. The receptors of IL-8 are the seven-helical G-protein coupled receptors CXCR1 and CXCR2, exclusively expressed on neutrophils. The functions of IL-8 are to induce rapid changes in cellular shape, activate the integrins, and release the granule contents of neutrophils. Thus, IL-8 can enhance the antimicrobial actions of defense cells.
Recombinant human I Interleukin-8/CXCL8 (rhIL-8) produced in E. coli is a single non-glycosylated polypeptide chain containing 72 amino acids. A fully biologically active molecule, rhIL-8 has a molecular mass of 8.4 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at ExCell Bio.
 
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